Cases of Keratoconus (Conical Cornea)

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Posterior conical cornea.

SINCE this condition was first described (Butler, 1930), only a handful ofcases has been added to the literature. In view of its infrequency, some cases are presented and compared with previous descriptions. Perhaps the name, although anatomically descriptive, is unfortunate, for it would imply that the condition has some relationship with the better-known conical cornea. In fact, there is no e...

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Keratoconus experimentally produced in mice using collagenase

Introduction: Keratoconus is a relatively common disease of cornea in which structural changes within the cornea cause it to thin and change to a conical shape and scar at the central portion of cornea. So far, few methods and drug treatments were introduced due to both lack of accepted animal models to induce experimental keratoconus and limitation of research in human considering ethical issu...

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Ultrastructural study of peripheral and central stroma of keratoconus cornea.

PURPOSE Assess the lamellar organisation of the peripheral and central stroma of the keratoconus (KC) and normal cornea. METHODS Five normal and three KC corneas were fixed in 2.5% glutaraldehyde and processed for electron microscopy. The ultrathin sections were observed under JEOL 1400 TEM, and digital images were taken with a bottom-mounted 11-megapixel Quamisa camera, using the iTEM softwa...

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Second-harmonic imaging microscopy of normal human and keratoconus cornea.

PURPOSE The purpose of this study was to evaluate the ability of second-harmonic imaging to identify differences in corneal stromal collagen organization between normal human and keratoconus corneas. METHODS Six normal corneas from eye bank donors and 13 corneas of patients with keratoconus, obtained after penetrating keratoplasty were examined. A femtosecond titanium-sapphire laser with 800-...

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Fibrillary lines of the cornea. A clinical sign in keratoconus.

Fibrillary lines, whether in the normal cornea or in keratoconus, are faint structures which must be searched for diligently with the appropriate biomicroscopical settings, using a high magnification and oblique focal illumination of high intensity. They are unlikely to be confused with other superficial linear changes in the cornea, such as mare's tail epithelial lines, fingerprint lines and t...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1914

ISSN: 0035-9157

DOI: 10.1177/003591571400701752